Sacubitril-Valsartan (Entresto) 100mg Film-Coated Tablets (28's) is a combination medication used primarily for the treatment of heart failure with reduced ejection fraction (HFrEF). It contains two active ingredients: Sacubitril, which inhibits neprilysin, an enzyme that breaks down beneficial natriuretic peptides, and Valsartan, an angiotensin II receptor blocker (ARB) that helps relax blood vessels and reduce blood pressure. Together, they work to improve heart function, reduce symptoms, and decrease the risk of hospitalization and death due to heart failure. The pack contains 28 tablets, typically providing a one-month supply when taken as prescribed.