Clonidine Hydrochloride (Clodin 75) 75mcg Tablets are used primarily to treat high blood pressure (hypertension) and may also be used to manage withdrawal symptoms from opioids or to address certain behavioral conditions. Each tablet contains 75mcg of clonidine, an alpha-2 adrenergic agonist that works by decreasing nerve signals in the brain, leading to reduced blood pressure and heart rate. The medication comes in a bottle of 100 tablets and is typically prescribed as part of a broader treatment plan.